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Eligibility depends on the specific medication, body mass index, weight-related medical conditions, treatment history, contraindications, pregnancy status and other individual factors

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I think we should prioritize tirzepatide, followed by the GLP-1 receptor agonists whenever possible, especially in patients where they have coexisting cardiometabolic diseases. Safety findings Naltrexone 32 mg/bupropion 360 mg was the only drug conferring a higher risk for any adverse event compared with placebo (RR = 1.45

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