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Focused ultrasound-mediated drug delivery in humans A path towards translation in neurodegenerative diseases

iPamorelin acts in two ways

TH is expressed only in CA (DA, NE, and epinephrine)-producing cells, i.e., CA neurons in the brain, NE neurons in the peripheral sympathetic nerves, and epinephrine and NE cells in the adrenal medulla (Nagatsu 2006)

The maintenance dose of this drug is 2.4 mg