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Regarding thyroid safety: animal studies with GLP-1 receptor agonists have identified thyroid C-cell changes in rodents

This could be a game-changing move, as its of course much more convenient from a patient perspective to take a pill than an injection a fact that has deterred some people away from GLP-1s in the past

Studies in the Journal of Diabetes, Obesity, and Metabolism dating back to 2017 have shown that these products risk of gastrointestinal problems was higher when the drug was prescribed at higher doses, for longer durations, and with weight loss

Wang B, Chandrasekera PC, Pippin JJ

Wegovy and gallstone risk Research suggests that Wegovy slightly increases the risk of gallbladder problems, including gallstones