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SUSTAIN-6, 2016 GLP-1 receptor signaling in the hypothalamus and hindbrain modulates satiety and food-reward pathways, a focus of ongoing neuroscience research

Some people report mild issues such as injection-site irritation, headaches, nausea, fatigue, or water retention

Some doctors prescribe B12 shots for people with low B12 levels or conditions that make it hard to absorb B12 from foods and supplements

This could be helpful for someone who prefers not to have injections

However, its use is primarily for research purposes, and further studies are needed to fully understand its long-term effects and applications before it is approved by drug administration agencies or the FDA