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Upon hypoxia, HIF-1 is stabilized and translocates to the nucleus, where it dimerizes with HIF-1, binds to target genes, and activates gene transcription

In our study exercise induced an increase in cellular oxidative stress (as shown by the increase in LPO content) and NO levels, and these factors could account for the increase in oxidative stress

Dual-emission ratiometric probes improve detection accuracy and can internally correct for changes in excitation conditions or detector performance

doi: 10.1093/rheumatology/keaa111.197 11 HoCTKMokCCCheungTTKwokKYYipRML

Certain peptides are shown to regulate appetite and increase fat metabolism