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A dermatologist can detect and remove them using liquid nitrogen therapy (cryotherapy)

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Simultaneously, some cells undergo cell cycle arrest and become senescent owing to the inhibition of cyclin-dependent kinases mediated by p21 activation through the DDR pathway 11

Overall, food cravings assessed during fasting also decreased with tirzepatide treatment compared with placebo, including cravings for sweets, high-fat food, carbohydrates, starches, and fast-food fats, while cravings for fruits and vegetables were not impacted by tirzepatide treatment