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Certain natural plant compounds have been shown to support GLP-1 production in lab and animal studies: Flavonoids like (-)-epicatechin (found in dark chocolate) and anthocyanins (from berries and purple veggies) have been shown to increase GLP-1 and improve metabolism via the PKA signaling pathway (Cremonini et al., 2021)

Therefore, medications like Mounjaro that can effectively support weight loss efforts have the potential to significantly improve the health outcomes of individuals with type 2 diabetes

The difference in change from T0 to T30 was measured

More recently Yonezawa et al