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The primary risks include increased hypoglycemia risk (especially with insulin or sulfonylureas), additive gastrointestinal symptoms such as nausea and diarrhea, and unknown effects on medication absorption due to tirzepatide's delayed gastric emptying

Effects of liraglutide combined with short-term continuous subcutaneous insulin infusion on glycemic control and beta cell function in patients with newly diagnosed type 2 diabetes mellitus: a pilot study

Rishi Seth