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Sedating Antihistamines (Diphenhydramine/Doxylamine) Mechanism: Antihistamines block H1 receptors, causing drowsiness

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The nonenzymatic antioxidants ascorbate (AsA) and glutathione (GSH), their respective oxidized formsdehydroascorbate (DHA) and glutathione disulphide (GSSG) and the enzymes that continuously recycle them constitute the major ROS scavenging system in plantsthe ascorbateglutathione cycle

As a result, they may miss out on the positive health benefits, including lowering diabetes risk, improving cardiovascular health, and reducing inflammation