On further assessment, six astronauts had abnormalities on eye examination, including optic disc oedema, folds in the choroid layer of the retina, flattening of the posterior eye, cotton wool spots and retinal nerve fibre layer thickening on optical coherence tomography (OCT) imaging
However, if you are using oral contraception, you should consider using a barrier method like condoms as well or switch to a non-oral contraceptive method for 4 weeks after starting Mounjaro and then for 4 weeks after each dose increase
Phys 15 , 1026310270 (2015)
doi: 10.3389/fmicb.2025.1685962 Received 28 August 2025 Accepted 27 October 2025 Published 12 November 2025 Volume 16 - 2025 Edited by Vikash Kumar, Central Inland Fisheries Research Institute (ICAR), India Reviewed by Sijie Wang, Affiliated Hospital of Guangdong Medical College Hospital, China Xuchang Zhou, The First Affiliated Hospital of Xiamen University, China Updates Copyright 2025 Wang, Xu, Zha and Wu
[DOI] [PubMed] [Google Scholar] Kavanagh JJ, Spriggs D, Bookman M, Ozols R, Gershenson DM, Han J, Lewis L, Brown GL, Dombrowski J, Maack C, Macpherson J, Lane A, Woodrow P and Henner WD