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In a double-blind, placebo-controlled study, a total of 1246 patients with mild to moderate hypertension received treatments of 2 combinations of amlodipine and valsartan (10 mg/160 mg, 10 mg/320 mg), or amlodipine alone (10 mg), valsartan alone (160 mg or 320 mg) or placebo

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Seine Plasmakonzentration liegt bei jungen Erwachsenen (etwa 20 Jahre) bei circa 200 ng/ml, sinkt aber bis zum Alter von etwa 60 Jahren auf rund 80 ng/ml

Drug Alchol Depend 142C:105109 Ethics declarations Conflict of interest The author(s) declare that they have no conflict of interest