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Lindqvist et al., 2017

This effect arises in part due to IgG4 blocking of IgE receptor binding and to an anti-inflammatory effect mediated through IgG4 signaling via Fc-gamma receptor II-beta (FcRII)

Or should we start thinking more seriously about body composition, adiposity, lean mass, sex differences, metabolic phenotype, etc

Quercetin, coenzyme Q10, and L-canavanine as protective agents against lipid peroxidation and nitric oxide generation in endotoxin-induced shock in rat brain.Pharmacol.Res20014325763 101