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Owners should be aware that adverse reactions may occur following administration of CLARO and should be instructed to observe the dog for signs such as ear pain and irritation, vomiting, head shaking, head tilt, incoordination, eye pain and ocular discharge (see Post-Approval Experience)

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Altogether, the data on OS in radiation nephropathy show clear evidence, that OS plays an important role in damaging the DNA promptly after irradiation

Im comfortable with those safety margins

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