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But like any performance-enhancing compound, its not without caveats: Appetite stimulation and water retention can affect certain users Long-term use may impact insulin sensitivity MK-677 remains unapproved by the FDA , and should be used only for research purposes MK-677 has demonstrated significant potential as a GH replacement therapy without the suppressive effects of exogenous hGH. Smith et al., The Journal of Clinical Endocrinology & Metabolism Current Clinical Development Ibutamoren is currently under Phase II clinical trials by Lumos Pharma for the treatment of growth hormone deficiency (GHD)

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Keep in a cool, dry, well-ventilated area away from incompatible substances

Gagnon et al