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Pertinently, premature aging syndromes such as Hutchinson-Gilford progeria syndrome (HGPS), Werner syndrome, Bloom syndrome, Cockayne syndrome and ataxia telangiectasia are characterized by genomic instability

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Peripheral vascular thrombosis has also occurred

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Differences between two groups were evaluated using t-tests, and comparisons among multiple groups were performed using one-way analysis of variance with Bonferroni post hoc test