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Proposed targets include the dysbiotic microbial composition, small intestinal bacterial overgrowth (SIBO) that is often associated with IBS, and post-infectious alterations ( Lactobacillus and Bifidobacterium compared to placebo, when it comes to reducing global IBS symptom scores and abdominal pain (Figure 3 describes examples of different probiotics that have been tested in RCTs and which GI symptom(s) they are targeting

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However, because NAC can occasionally cause mild gastrointestinal irritation, patients with sensitive stomachs may need to compromise and take it with a light carbohydrate snack