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The crystals appeared in 200300 mM ammonium formate, 36% PEG400, 510% (w/v) guanidine hydrochloride, pH 6.26.6 after 7 days and reached their biggest size (~150 m) in 1 month

The results of phase 2 (dose-ranging) trials with primary endpoints of HbA 1c change (Rosenstock et al, 2023) and body-weight change (Jastreboff et al, 2023) are shown in Table 6

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