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"The ingredients may interact in a dangerous way with professionally-prescribed treatments

Your doctor will check kidney and liver function thoroughly before you start, and repeat the tests on a tighter schedule once you're on it

A 2025 matched-cohort study found men who started testosterone therapy had significantly higher rates of tendon tears and repairs at one and two years compared to controls, a pattern the authors attributed to testosterone's effect on tendon biomechanics outpacing the tissue's regenerative capacity Sherman et al

Patients should always consult their GP or specialist before considering any unlicensed treatment, and should only receive retatrutide within the context of a regulated clinical trial or under appropriate medical supervision

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