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Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylure

Park S, Ahn G, Park J, Seo S

27, at UT Southwestern Medical Center

But I think we just have to think about what are some of the other potential problems that could arise from these drugs. Schrack says older adults who may have issues with balance or bone mass should be mindful that the weight loss on these medications may cause the loss of muscle, not just fat, which may affect stability and fracture risk

Adverse events were significantly higher with Resmetirom (RR 1.47, 95% CI: 1.24 to 1.74), while GLP-1 and FGF21 showed non-significant trends towards increased risk