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It is a complex metabolic disease characterized by insulin resistance, progressive beta-cell dysfunction, chronic inflammation, and an increased risk of cardiovascular disease, kidney disease, neuropathy, retinopathy, and other long-term complications

Pedro Mezquita-Raya has the following financial relationships: advisor on scientific boards for Abbott, Astra-Zeneca, FAES and Novo-Nordisk

If the plasma level is in the high-risk region of the nomogram, the risk of developing hepatotoxicity is 60% or higher, and antidote therapy is warranted

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