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La evidencia sobre la utilidad de la terapia sistmica es limitada: los estudios son en su mayora de pequeo tamao, de reducida duracin, incluyen a mujeres de manera mayoritaria, la metodologa de evaluacin es heterognea y no hay parmetros consensuados de respuesta clnica relevante

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BV can be used topically or subcutaneously on wounds (Table 4)

Relative quantification (RQ) of TGF- expression was calculated using the Ct method, normalized to GAPDH 46

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