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You could also consider a SAMe supplement, but bear in mind it is a medicine in some countries, and there is some evidence that it can imbalance the system and downregulate endogenous SAMe synthesis

We encourage our patients to view these injections as a supportive tool rather than a magic solution

Nat Rev Microbiol 19(1):5571 Ruuskanen MO, Erawijantari PP, Havulinna AS, Liu Y, Mric G, Tuomilehto J et al (2022) Gut microbiome composition is predictive of incident type 2 diabetes in a population cohort of 5572 Finnish adults