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Ongoing trials assessing predictive biomarkers and less invasive monitoring methods seek to address these limitations and enhance patient outcomes, though high costs and limited access continue to restrict broader application of effective treatments like liposomal formulations

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AGEs may also compromise antioxidant defenses by modifying or inactivating key enzymatic antioxidants, including superoxide dismutase and glutathione peroxidases 48,49,50

doi: 10.1186/s12974-024-03285-3 62 ThimmappaPYVasishtaSGaneshKNairASJoshiMB

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